Who goes to a Chiropractor? What has your experience been like?

massarogi · 15 days

If you've ever actually played a contact sport and been adjusted you know how amazing those guys are for fixing acute injuries cases by impact. Go and feel for yourself, the commenters here belittling them are clueless

imagoodusername · 15 days

Front squats are worlds safer for your back, not even an argument to make

downtown14 · 1 month

And it's not like border collies are a separate species from pitbulls, but uh...

libbykino · 1 month

What in the fuck did I just watch. As much as there is to the plot why in the actual fuck do they need further reinforcement about Joffery being abhorrent and the guards at Harenhall being sadistic?

Is HBO just trying to see how uncomfortable they can make people?

I'm surprised the damn shadow-baby birthing wasn't something closer to 2 girls 1 cup. How is this good television?

It's just edgy - not good.

Ayatrollah_Umadi · 1 month

Front squats are ultimately a lot safer, but regardless he's a moron.

dirkadirk2011 · 2 months

Hang in there and keep your head up, hopefully you'll keep him from ever doing it to another girl again

MonkeyProcess · 2 months

Jurassic Park is a solid read, but The Water is Wide would hit closer to home.

banjati · 2 months

That you're probably not someone I'd want to get to know too well, since the Muslim world's biggest barrier to modernity is treating women like chattel and like it or not the hijab symbolizes that. A hijab doesn't indemnify you against Western sexuality, it just reminds Western men how Muslim men are legally allowed to treat their females.

Seeing a woman wear one screams "self-important," if you want to be pious simply live a moral and compassionate life.

So I'd have as much urge to develop a close and continuing relationship with you as I would a nun.

ohheyboo · 3 months

You're seriously going to parse my use of "pretty definitively" instead of editing your top-voted comment to give vitamin D a little love? Of course researchers are going to couch their assertions they pretty much have to, but I don't think that really changes what the research is indicating.

Apparently much of the globe is running a deficiency, which makes sense given the modern office lifestyle - you don't think it would make sense to spread awareness about its likely beneficial immune effects?

ohheyboo · 3 months

I don't have a comprehensive way to search Nature's back-issues, the jury might technically still be out since it takes fucking forever for any kind of consensus to be reached in the community, but I think vitamin D deserves at least a nod in your top level comment since, as noted below, it seems much of the world population is likely running a vitamin D deficiency:

Indeed, it is only in recent years that a much clearer picture of the role of vitamin D as a determinant of immune responsiveness has emerged. Two new concepts have prompted this change. Firstly studies of innate immunity have shown that intracrine induction of antimicrobial activity by vitamin D is a pivotal component of monocyte/macrophage response to infection. Secondly, it is now clear that sub-optimal vitamin D status is a common feature of many populations throughout the world, with the potential to compromise monocyte/macrophage metabolism of 25OHD and subsequent actions of 1,25(OH)(2)D.
Vitamin D has a critical role in the innate immune system through the production of antimicrobial peptides - particularly cathelicidin. Vitamin D would appear to have an important role in respiratory tract, skin and potentially gut health. A number of autoimmune diseases, including multiple sclerosis, Type I diabetes, systemic lupus erythematosus and rheumatoid arthritis, are associated with vitamin D deficiency.
However, recent reports have supported a role for 1,25(OH)(2)D(3) in mediating normal function of the innate and adaptive immune systems. Crucially, these effects seem to be mediated via localized autocrine or paracrine synthesis of 1,25(OH)(2)D(3) from precursor 25-hydroxyvitamin D(3), the main circulating metabolite of vitamin D. The ability of vitamin D to influence normal human immunity is highly dependent on the vitamin D status of individuals, and may lead to aberrant response to infection or autoimmunity in those who are lacking vitamin D. The potential health significance of this has been underlined by increasing awareness of impaired vitamin D status in populations across the globe.
Both the vitamin D receptor and CYP27B1 can be constitutive or induced by the ligands that activate the immune processes in these cells, providing feedback loops that help regulate the immune response. In general, 1,25(OH)(2)D(3) suppresses most elements of the adaptive immune system while inducing most elements of the innate immune system. Thus 1,25(OH)(2)D(3) may be protective against various autoimmune diseases and may limit graft rejection by suppressing adaptive immunity while enhancing the first line of defense against invading microorganisms via upregulation of innate immunity.

...if you don't mind me asking, how exactly does this fall short of "definitively" in your opinion?

ohheyboo · 3 months

Vitamin D pretty definitively does:

A short while later, a group of scientists from UCLA published a remarkable paper in the prestigious journal, Nature. The UCLA group confirmed two other recent studies, showing that a naturally occurring steroid hormone - a hormone most of us take for granted - was, in effect, a potent antibiotic. Instead of directly killing bacteria and viruses, the steroid hormone under question increases the body's production of a remarkable class of proteins, called antimicrobial peptides. The 200 known antimicrobial peptides directly and rapidly destroy the cell walls of bacteria, fungi, and viruses, including the influenza virus, and play a key role in keeping the lungs free of infection. The steroid hormone that showed these remarkable antibiotic properties was plain old vitamin D.

http://www.medicalnewstoday.com/articles/51913.php

ohheyboo · 3 months

Vitamin D pretty definitively does:

A short while later, a group of scientists from UCLA published a remarkable paper in the prestigious journal, Nature. The UCLA group confirmed two other recent studies, showing that a naturally occurring steroid hormone - a hormone most of us take for granted - was, in effect, a potent antibiotic. Instead of directly killing bacteria and viruses, the steroid hormone under question increases the body's production of a remarkable class of proteins, called antimicrobial peptides. The 200 known antimicrobial peptides directly and rapidly destroy the cell walls of bacteria, fungi, and viruses, including the influenza virus, and play a key role in keeping the lungs free of infection. The steroid hormone that showed these remarkable antibiotic properties was plain old vitamin D.

http://www.medicalnewstoday.com/articles/51913.php

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